Virus Spike vs. Vaccine Spike: differences

Dr. Mikolaj Raszek

In this video we describe the spike protein in detail from a molecular point of view and reveal its amazing complexity. We compare how the spike protein from mRNA vaccines differs from those occurring naturally as presented by the SARS-CoV-2 virus. Discussed content: Virus vs vaccine spike: https://www.nature.com/articles/s4154… Furin cleavage: https://journals.plos.org/plospathoge… Receptor binding: https://www.nature.com/articles/s4158… Fusion peptide: https://pubs.acs.org/doi/10.1021/jacs… Post fusion structure: https://www.pnas.org/content/118/48/e… Prolines impact: https://www.science.org/doi/10.1126/s… Vaccine designs: https://www.frontiersin.org/articles/…